Several commentators on this blog recently have stated that they believe the first 100 pages of Human Action to be absurd. I don't find their statements persuasive. I believe Mises's work in methodology to be profound contributions to the human sciences. We have to remember that Mises was carving out not only a scientific niche for economics, but attempting to defend economics as a human science that would avoid the pitfalls of "mechanomorphism" and "scientism" on the one hand, and "historicism" on the other. He was endorsing the critique of methodological monism that was raised by the "cultural sciences" in German language scholarship, and yet arguing against those writers that there was in fact a universal science of economics. He was continuing the project first begun by Menger, and in my opinion he refined the argument and improved upon it.
Here is a recent attempt by Pete Leeson and myself to explain Mises's methodological position and its importance to our peers within the economics profession.